search

UMD     This Site





Professor S.K. Gupta (ME/ISR) is the principal investigator for a three-year, $550K National Science Foundation grant, ?Image Guided Autonomous Optical Manipulation of Cell Groups.? Associate Professor Wolfgang Losert (Physics) is the co-PI.

The research team will create a computational foundation, methods, and tools for efficient and autonomous optical micromanipulation using microsphere ensembles as grippers. This system will make use of a holographic optical tweezer, which uses multiple focused optical traps to position microspheres in three-dimensional space. The research will provide:

?An experimentally validated optical-tweezers based workstation for concurrent manipulation of multiple cells.

?Algorithms for on-line monitoring of workspace to support autonomous manipulation

?Real-time image-guided motion planning strategies for transporting microspheres ensembles.

Gupta and Losert?s work will provide a new way to autonomously manipulate difficult-to-trap or sensitive objects using microspheres ensembles as reconfigurable grippers. It also will lead to fundamental advances in several cyber physical systems areas by providing new approaches to micromanipulations, fast and accurate algorithms with known uncertainty bounds for on-line monitoring of moving microscale objects, and real-time motion planning algorithms to transport particle ensembles.

The ability to quickly and accurately manipulate individual cells with minimal training will enable researchers to conduct basic research at the cellular scale. Control over cell-cell interactions will allow unprecedented insights into cell signaling pathways and open up new avenues for medical diagnosis and treatment.



Related Articles:
Sagar Chowdhury wins ISR graduate student award
Ray-tracing paper wins 'Best of Conference' at 2012 IDETC/CIE
Six Clark School Faculty Receive 2024 DURIP Awards
Maryland Engineers Awarded Grants to Address Humanity's Grand Challenges
Big Ten Network spotlights Maryland Engineering
Deepfake Detection Invention Discerns Between Real and Fake Media
Improving Fairness and Trust in AI Used for College Admissions and Language Translation
UMD Autonomous Navigation Research Featured in Tech Explore
Manocha Receives 2022 Verisk AI Faculty Research Award
Gemstone Honors Program Marks 25th Anniversary

September 28, 2009


«Previous Story  

 

 

Current Headlines

Remembering Rance Cleaveland (1961-2024)

Dinesh Manocha Inducted into IEEE VGTC Virtual Reality Academy

ECE Ph.D. Student Ayooluwa (“Ayo”) Ajiboye Recognized at APEC 2024

Balachandran, Cameron, Yu Receive 2024 MURI Award

UMD, Booz Allen Hamilton Announce Collaboration with MMEC

New Research Suggests Gossip “Not Always a Bad Thing”

Ingestible Capsule Technology Research on Front Cover of Journal

Governor’s Cabinet Meeting Features Peek into Southern Maryland Research and Collaboration

Celebrating the Impact of Black Maryland Engineers and Leaders

Six Clark School Faculty Receive 2024 DURIP Awards

 
 
Back to top  
Home Clark School Home UMD Home